Emergency services were called to reports a truck struck a pedestrian on Murray Road, Preston about 7.20am.

The pedestrian, a 60-year-old Preston woman, was taken to hospital with serious injuries.

The driver of the truck, a 33-year-old Thomastown man, stopped at the scene.

He is currently assisting police with their enquiries.

Investigators are hoping to speak with anyone who witnessed the incident or may have dash-cam vision of the incident or truck leading up to the collision.

Anyone with information or who may have witnessed the collision is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report at www.crimestoppersvic.com.au.