It’s believed a Ford stationwagon had been travelling north on Elora Road when it was struck by a motorcycle travelling east along Centre Road about 6.15am.

The motorcycle rider, an unidentified man, was taken to hospital with life threatening injuries but died soon after.

Police have arrested the driver of the Ford, a 53-year-old Oakleigh South man, who is assisting with enquiries.

Major Collision Investigation Unit detectives are investigating and would like to speak to anyone who may have witnessed the collision.

Police are urging anyone who may have witnessed the collision or who may have information to contact Crime Stoppers on 1800 333 000 or submit a confidential report at www.crimestoppersvic.com.au

Lives lost

2016:  198

2015: 170